Recombinant Human Periodic tryptophan protein 1 homolog (PWP1)

Code CSB-YP615707HU
MSDS
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Source Yeast
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Code CSB-EP615707HU
MSDS
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Source E.coli
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Code CSB-EP615707HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP615707HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP615707HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PWP1
Uniprot No.
Alternative Names
Keratinocyte protein IEF SSP 9502; Periodic tryptophan protein 1 homolog; PWP1; PWP1 homolog; PWP1_HUMAN
Species
Homo sapiens (Human)
Expression Region
1-501
Target Protein Sequence
MNRSRQVTCV AWVRCGVAKE TPDKVELSKE EVKRLIAEAK EKLQEEGGGS DEEETGSPSE DGMQSARTQA RPREPLEDGD PEDDRTLDDD ELAEYDLDKY DEEGDPDAET LGESLLGLTV YGSNDQDPYV TLKDTEQYER EDFLIKPSDN LIVCGRAEQD QCNLEVHVYN QEEDSFYVHH DILLSAYPLS VEWLNFDPSP DDSTGNYIAV GNMTPVIEVW DLDIVDSLEP VFTLGSKLSK KKKKKGKKSS SAEGHTDAVL DLSWNKLIRN VLASASADNT VILWDMSLGK PAASLAVHTD KVQTLQFHPF EAQTLISGSY DKSVALYDCR SPDESHRMWR FSGQIERVTW NHFSPCHFLA STDDGFVYNL DARSDKPIFT LNAHNDEISG LDLSSQIKGC LVTASADKYV KIWDILGDRP SLVHSRDMKM GVLFCSSCCP DLPFIYAFGG QKEGLRVWDI STVSSVNEAF GRRERLVLGS ARNSSISGPF GSRSSDTPME S
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.
Gene References into Functions
  1. High PWP1 expression is associated with head and neck squamous cell carcinoma. PMID: 29065309
  2. Endonuclein interacts with several proteins indicating a broad function including signal transduction and chaperone activity PMID: 20028516
Subcellular Location
Nucleus. Nucleus, nucleolus. Chromosome.
Protein Families
WD repeat PWP1 family
Tissue Specificity
High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.
Database Links

HGNC: 17015

KEGG: hsa:11137

STRING: 9606.ENSP00000387365

UniGene: Hs.506652

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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