Recombinant Human Phosphatidylcholine transfer protein (PCTP)

Code CSB-YP017651HU
MSDS
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Source Yeast
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Code CSB-EP017651HU
MSDS
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Source E.coli
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Code CSB-EP017651HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP017651HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP017651HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PCTP
Uniprot No.
Alternative Names
PC TP; PC-TP; PCTP; Phosphatidylcholine transfer protein; PPCT_HUMAN; StAR related lipid transfer (START) domain containing 2; StAR related lipid transfer protein 2; StAR-related lipid transfer protein 2; STARD 2; StARD2; START domain containing 2; START domain containing protein 2; START domain-containing protein 2
Species
Homo sapiens (Human)
Expression Region
1-214
Target Protein Sequence
MELAAGSFSE EQFWEACAEL QQPALAGADW QLLVETSGIS IYRLLDKKTG LYEYKVFGVL EDCSPTLLAD IYMDSDYRKQ WDQYVKELYE QECNGETVVY WEVKYPFPMS NRDYVYLRQR RDLDMEGRKI HVILARSTSM PQLGERSGVI RVKQYKQSLA IESDGKKGSK VFMYYFDNPG GQIPSWLINW AAKNGVPNFL KDMARACQNY LKKT
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
Gene References into Functions
  1. Identified the variant rs2912553 as contributing to racially differential expression of PCTP. PMID: 28251237
  2. Mutations in PCTP gene is associated with prostate cancer PMID: 26585945
  3. PC-TP contributes to the racial difference in PAR4-mediated platelet activation. PMID: 24216752
  4. crystal structures of human PC-TP in complex with dilinoleoyl-PtdCho or palmitoyl-linoleoyl-PtdCho reveal that a single well-ordered PtdCho molecule occupies a centrally located tunnel PMID: 12055623
  5. phosphatidylcholine transfer protein gene variants are associated with LDL-peak particle size PMID: 17266964

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Subcellular Location
Cytoplasm.
Tissue Specificity
Highest expression in liver, placenta, testis, kidney and heart. Low levels in brain and lung. No expression detected in thymus.
Database Links

HGNC: 8752

OMIM: 606055

KEGG: hsa:58488

STRING: 9606.ENSP00000268896

UniGene: Hs.285218

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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