Recombinant Human Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PIP5KL1)

Code CSB-YP719415HU
MSDS
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Source Yeast
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Code CSB-EP719415HU
MSDS
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Source E.coli
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Code CSB-EP719415HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP719415HU
MSDS
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Source Baculovirus
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Code CSB-MP719415HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PIP5KL1
Uniprot No.
Alternative Names
PIP5KL1; Phosphatidylinositol 4-phosphate 5-kinase-like protein 1; PI(4)P 5-kinase-like protein 1; PtdIns(4)P-5-kinase-like protein 1; EC 2.7.1.68
Species
Homo sapiens (Human)
Expression Region
1-394
Target Protein Sequence
MAAPSPGPRE VLAPSPEAGC RAVTSSRRGL LWRLRDKQSR LGLFEISPGH ELHGMTCMMQ AGLWAATQVS MDHPPTGPPS RDDFSEVLTQ VHEGFELGTL AGPAFAWLRR SLGLAEEDYQ AALGPGGPYL QFLSTSKSKA SFFLSHDQRF FLKTQGRREV QALLAHLPRY VQHLQRHPHS LLARLLGVHS LRVDRGKKTY FIVMQSVFYP AGRISERYDI KGCEVSRWVD PAPEGSPLVL VLKDLNFQGK TINLGPQRSW FLRQMELDTT FLRELNVLDY SLLIAFQRLH EDERGPGSSL IFRTARSVQG AQSPEESRAQ NRRLLPDAPN ALHILDGPEQ RYFLGVVDLA TVYGLRKRLE HLWKTLRYPG RTFSTVSPAR YARRLCQWVE AHTE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3.
Gene References into Functions
  1. These studies indicate a functional negative correlation between elevated levels of PIP5KL1 and the development of human gastric cancer. PMID: 19680787
  2. PIPKH acts as a scaffold to localize and regulate type I PI(4)P 5-kinases and the synthesis of PI(3,4,5)P(3) PMID: 14701839
Subcellular Location
Cytoplasm. Membrane.
Database Links

HGNC: 28711

OMIM: 612865

KEGG: hsa:138429

STRING: 9606.ENSP00000373399

UniGene: Hs.734928

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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