Recombinant Human Sodium-coupled neutral amino acid transporter 5 (SLC38A5), partial

Code CSB-YP837853HU
MSDS
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Source Yeast
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Code CSB-EP837853HU
MSDS
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Source E.coli
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Code CSB-EP837853HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP837853HU
MSDS
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Source Baculovirus
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Code CSB-MP837853HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SLC38A5
Uniprot No.
Alternative Names
Amino acid transporter system N2; JM 24; JM24; pp7194; S38A5; S38A5_HUMAN; Slc38a5; SLC8 A5; SLC8A 5; SN 2; SN2; SNAT 5; SNAT5; Sodium coupled neutral amino acid transporter 5; Sodium coupled neutral amino acid transporter5; Sodium-coupled neutral amino acid transporter 5; Solute carrier family 38 member 5; Solute carrier family 38 member5; System N transporter 2; System N transporter2
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH-sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium.
Gene References into Functions
  1. Confirmed by mRNA and protein expression, the amino acid transporters SLC7A7 and SLC38A5 showed marked differences between controls and intrauterine growth restriction/pre-eclampsia and were regulated by both diseases. In contrast, ABCA1 may play an exclusive role in the development of pre-eclempsia. PMID: 29499643
  2. A 50kb deletion at Xp11.23 including the two genes, SLC38A5 and FTSJ1 was found in 3 brothers with moderate to severe mental retardation. PMID: 17333282
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Amino acid/polyamine transporter 2 family
Tissue Specificity
Predominantly expressed in stomach, brain, liver, lung and intestinal tract.
Database Links

HGNC: 18070

OMIM: 300649

KEGG: hsa:92745

STRING: 9606.ENSP00000313740

UniGene: Hs.195155

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