Recombinant Human Sodium-dependent serotonin transporter(SLC6A4),partial,Yeast

Code CSB-YP021702HU
Product Type Recombinant Protein
Size Pls inquiry other sizes
Uniprot No. P31645
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity >85% (SDS-PAGE)
Source Yeast
Gene Names SLC6A4
Protein Names Recommended name: Sodium-dependent serotonin transporter Alternative name(s): 5HT transporter Short name= 5HTT Solute carrier family 6 member 4
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Product Info The following tags are available.
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
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Function Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
Subcellular Location Cell membrane, Multi-pass membrane protein, Endomembrane system, Multi-pass membrane protein, Endosome membrane, Multi-pass membrane protein
Protein Families Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A4 subfamily
Tissue Specificity Expressed in platelets (at protein level).
Database Links

HGNC: 11050

OMIM: 103780

KEGG: hsa:6532

STRING: 9606.ENSP00000261707

UniGene: Hs.134662

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