Recombinant Human Steroidogenic factor 1(NR5A1),partial

In Stock
Code CSB-EP623795HU
Product Type Recombinant Protein
Size EP: USD1459
Uniprot No. Q13285
Abbreviation NR5A1
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity Greater than 85% as determined by SDS-PAGE.
Sequence SGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
Research Area Developmental Biology
Source E.coli
Gene Names NR5A1
Protein Names Recommended name: Steroidogenic factor 1 Short name= SF-1 Short name= STF-1 Alternative name(s): Adrenal 4-binding protein Fushi tarazu factor homolog 1 Nuclear receptor subfamily 5 group A member 1 Steroid hormone recept
Expression Region 218-461aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 31.9 kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues
Involvement in disease 46,XY sex reversal 3 (SRXY3); 46,XX sex reversal 4 (SRXX4); Adrenal insufficiency, NR5A1-related (AINR); Premature ovarian failure 7 (POF7); Spermatogenic failure 8 (SPGF8)
Subcellular Location Nucleus
Protein Families Nuclear hormone receptor family, NR5 subfamily
Tissue Specificity High expressed in the adrenal cortex, the ovary, the testis, and the spleen (PubMed:9177385).
Database Links

HGNC: 7983

OMIM: 184757

KEGG: hsa:2516

STRING: 9606.ENSP00000362690

UniGene: Hs.495108

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