Purity
Greater than 90% as determined by SDS-PAGE.
Alternative Names
CD_antigen; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; SDC; Sdc1; SDC1_HUMAN; SYND1; Syndecan 1; Syndecan; syndecan proteoglycan 1; Syndecan-1
Species
Homo sapiens (Human)
Expression Region
23-254aa
Target Protein Sequence
QIVATNLPPEDQDGSGDDSDNFSGSGAGALQDITLSQQTPSTWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPKEGEAVVLPEVEPGLTAREQEATPRPRETTQLPTTHLASTTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLG
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Protein Length
Extracellular Domain
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
Amino acids 23-254 constitute the expression domain of recombinant Human SDC1. This SDC1 protein is expected to have a theoretical molecular weight of 39.9 kDa. Expression of this SDC1 protein is conducted in e.coli. The SDC1 coding gene included the N-terminal 6xHis-SUMO tag, which simplifies the detection and purification processes of the recombinant SDC1 protein in following stages of expression and purification.
Syndecan-1 (SDC1) is a cell surface proteoglycan that plays a crucial role in cell-matrix interactions, cell adhesion, and signaling. As a member of the syndecan family, SDC1 is involved in various physiological processes, including development, wound healing, and immune response. It acts as a coreceptor for growth factors and cytokines, mediating their signaling pathways. SDC1 also participates in cell adhesion by binding to extracellular matrix components. In cancer, SDC1 is often dysregulated and implicated in tumor progression, angiogenesis, and metastasis. Research on SDC1 spans multiple areas, including cancer biology, immunology, and developmental biology, aiming to understand its complex functions and potential therapeutic implications in various diseases.