Recombinant Human Testis-specific H1 histone (H1FNT)

Code CSB-YP762309HU
MSDS
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Source Yeast
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Code CSB-EP762309HU
MSDS
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Source E.coli
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Code CSB-EP762309HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP762309HU
MSDS
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Source Baculovirus
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Code CSB-MP762309HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
H1FNT
Uniprot No.
Alternative Names
H1 histone family member N testis specific; H1FNT; H1FNT_HUMAN; H1T2; HANP1; Haploid germ cell-specific nuclear protein 1; Histone H1t2; Testis-specific H1 histone
Species
Homo sapiens (Human)
Expression Region
1-255
Target Protein Sequence
MEQALTGEAQ SRWPRRGGSG AMAEAPGPSG ESRGHSATQL PAEKTVGGPS RGCSSSVLRV SQLVLQAIST HKGLTLAALK KELRNAGYEV RRKSGRHEAP RGQAKATLLR VSGSDAAGYF RVWKVPKPRR KPGRARQEEG TRAPWRTPAA PRSSRRRRQP LRKAARKARE VWRRNARAKA KANARARRTR RARPRAKEPP CARAKEEAGA TAADEGRGQA VKEDTTPRSG KDKRRSSKPR EEKQEPKKPA QRTIQ
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1.
Gene References into Functions
  1. h-HANP1 is expressed in the testes and its genomic construct also intronless as mouse Hanp1. We found that the h-HANP1 coding region have 5 single-nucleotide polymorphisms in Japanese men. PMID: 16533358
  2. H1T2 is a protein required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. PMID: 15710904
Subcellular Location
Nucleus. Chromosome.
Protein Families
Histone H1/H5 family
Tissue Specificity
Testis-specific.
Database Links

HGNC: 24893

KEGG: hsa:341567

STRING: 9606.ENSP00000334805

UniGene: Hs.155833

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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