Purity
Greater than 90% as determined by SDS-PAGE.
Research Area
Cell Biology
Alternative Names
Cell proliferation inducing gene 26 protein; Cell proliferation-inducing gene 26 protein; CGI 31; Growth inhibiting gene 11; PDIA12; PIG26; Protein disulfide isomerase family A; member 12; Thioredoxin domain containing protein 14; Thioredoxin domain-containing protein 14; Thioredoxin related transmembrane protein 2; Thioredoxin-related transmembrane protein 2; tmx2; TMX2_HUMAN; TXNDC14
Species
Homo sapiens (Human)
Expression Region
49-102aa
Target Protein Sequence
LPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANT
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Protein Length
Extracellular Domain
Tag Info
N-terminal GST-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
Amino acids 49-102 form the expressed segment for recombinant Human TMX2. The calculated molecular weight for this TMX2 protein is 33.3 kDa. The TMX2 protein was expressed in e.coli. The TMX2 coding gene included the N-terminal GST tag, which simplifies the detection and purification processes of the recombinant TMX2 protein in following stages of expression and purification.
Thioredoxin-related transmembrane protein 2 (TMX2) is a member of the thioredoxin superfamily, playing a role in redox regulation within the endoplasmic reticulum (ER). TMX2 contains a thioredoxin-like domain and multiple transmembrane helices, suggesting its association with the ER membrane. As part of the ER redox system, TMX2 is involved in maintaining protein folding and quality control by participating in disulfide bond formation and reduction. It may interact with other ER-resident proteins and contribute to the regulation of cellular responses to oxidative stress. Research on TMX2 spans various areas, including investigations into its specific redox functions, potential interactions with client proteins, and implications in cellular processes related to ER homeostasis.
