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Code | CSB-MP023686HUd9 |
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Size | $660 |
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The region for expressing recombinant Human TMEM119 contains amino acids 26–96. The expected molecular weight for the TMEM119 protein is calculated to be 36.3 kDa. The TMEM119 protein was expressed in mammalian cell. The C-terminal hFc tag was fused into the coding gene segment of TMEM119, making it easier to detect and purify the TMEM119 recombinant protein in the later stages of expression and purification.
The human transmembrane protein 119 (TMEM119) is a membrane-associated protein primarily expressed in microglia, which are immune cells in the central nervous system. TMEM119 serves as a marker for microglia, and its expression is associated with the homeostatic state of these cells. Microglia play crucial roles in immune responses within the brain and contribute to the maintenance of neural tissue integrity. Understanding TMEM119 expression and its association with microglial function is essential in unraveling the complex interactions between the immune system and the nervous system. Research on TMEM119 contributes to insights into microglial biology and its implications in neuroinflammatory and neurodegenerative conditions.There are currently no reviews for this product.