Recombinant Human UPF0544 protein C5orf45 (C5orf45)

Code CSB-YP747338HU
MSDS
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Source Yeast
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Code CSB-EP747338HU
MSDS
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Source E.coli
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Code CSB-EP747338HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP747338HU
MSDS
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Source Baculovirus
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Code CSB-MP747338HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
MRNIP
Uniprot No.
Alternative Names
MRNIP; C5orf45; MRN complex-interacting protein; MRN-interacting protein
Species
Homo sapiens (Human)
Expression Region
1-343
Target Protein Sequence
MASLQRSRVL RCCSCRLFQA HQVKKSVKWT CKACGEKQSF LQAYGEGSGA DCRRHVQKLN LLQGQVSELP LRSLEETVSA SEEENVGHQQ AGNVKQQEKS QPSESRWLKY LEKDSQELEL EGTGVCFSKQ PSSKMEEPGP RFSQDLPRKR KWSRSTVQPP CSRGVQDSGG SEVAWGPQKG QAGLTWKVKQ GSSPCLQENS ADCSAGELRG PGKELWSPIQ QVTATSSKWA QFVLPPRKSS HVDSEQPRSL QRDPRPAGPA QAKQGTPRAQ ASREGLSRPT AAVQLPRATH PVTSGSERPC GKTSWDARTP WAEGGPLVLE AQNPRPTRLC DLFITGEDFD DDV
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.
Gene References into Functions
  1. these data reveal that MRNIP is an important component of the human DNA damage response. PMID: 27568553
Subcellular Location
Nucleus. Nucleus, nucleoplasm.
Protein Families
MRNIP family
Database Links

HGNC: 30817

OMIM: 617154

KEGG: hsa:51149

STRING: 9606.ENSP00000292586

UniGene: Hs.741169

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