Recombinant Human Myeloid-derived growth factor (MYDGF)

Code CSB-YP842625HU
MSDS
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Source Yeast
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Code CSB-EP842625HU
MSDS
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Source E.coli
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Code CSB-EP842625HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP842625HU
MSDS
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Source Baculovirus
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Code CSB-MP842625HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
MYDGF
Uniprot No.
Alternative Names
C19orf10; Chromosome 19 open reading frame 10; CS010_HUMAN; EUROIMAGE1875335; IL 25; IL 27; IL-25; IL25; IL27; IL27w; Interleukin 25; Interleukin 27 working designation ; Interleukin-25; Interleukin25; R33729 1; R337291; SF20 ; Stromal cell derived growth factor; Stromal cell derived growth factor SF20; Stromal cell-derived growth factor SF20; Uncharacterized protein C19orf10 precursor; UPF0556 protein C19orf10
Species
Homo sapiens (Human)
Expression Region
32-173
Target Protein Sequence
VSEPTTVAF DVRPGGVVHS FSHNVGPGDK YTCMFTYASQ GGTNEQWQMS LGTSEDHQHF TCTIWRPQGK SYLYFTQFKA EVRGAEIEYA MAYSKAAFER ESDVPLKTEE FEVTKTAVAH RPGAFKAELS KLVIVAKASR TEL
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Gene References into Functions
  1. Bone marrow-derived monocytes and macrophages produce this protein endogenously to protect and repair the heart after myocardial infarction. PMID: 25581518
  2. Taken together, these data suggest that c19orf10 might be one of the growth factors and potential molecular targets activated in HCC. PMID: 21128247
  3. we identified a novel protein, c19orf10 (chromosome 19 open reading frame 10), produced by fibroblast-like synoviocytes PMID: 17362502
Subcellular Location
Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
Protein Families
MYDGF family
Tissue Specificity
Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
Database Links

HGNC: 16948

OMIM: 606746

KEGG: hsa:56005

STRING: 9606.ENSP00000262947

UniGene: Hs.465645

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