Human Myeloid-derived growth factor(MYDGF) ELISA kit

Code CSB-EL003433HU
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T
Uniprot No. Q969H8
Target Name Myeloid-derived growth factor
Species Human
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Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis
Subcellular Location Secreted, Endoplasmic reticulum-Golgi intermediate compartment
Protein Families MYDGF family
Tissue Specificity Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502).
Database Links

HGNC: 16948

OMIM: 606746

KEGG: hsa:56005

STRING: 9606.ENSP00000262947

UniGene: Hs.465645

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