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| Code | CSB-EP019259HU |
| Product Type | Recombinant Protein |
| Size |
US$1726Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P54725 |
| Relevance | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC.Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome. |
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| Storage Buffer | Tris-based buffer,50% glycerol |
| Species | Homo sapiens (Human) |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Sequence | MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVPIRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQFQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE |
| Research Area | Epigenetics and Nuclear Signaling |
| Source | E.coli |
| Gene Names | RAD23A |
| Expression Region | 1-363aa |
| Tag Info | N-terminal GST-tagged |
| Mol. Weight | 66.6kDa |
| Protein Description | Full Length |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
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| Function | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; FUNCTION |
| Subcellular Location | Nucleus |
| Protein Families | RAD23 family |
| Database Links |
HGNC: 9812 OMIM: 600061 KEGG: hsa:5886 STRING: 9606.ENSP00000467024 UniGene: Hs.643267 |
| Pathway | Protein processing in endoplasmic reticulum |
RAD23A Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA03774A0Rb | RAD23A Antibody | Human | ELISA, WB, IHC |
| CSB-PA03774B0Rb | RAD23A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA03774C0Rb | RAD23A Antibody, FITC conjugated | Human | ELISA |
| CSB-PA03774D0Rb | RAD23A Antibody, Biotin conjugated | Human | ELISA |
RAD23A Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA019259GA01HU | RAD23A Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA040140 | RAD23A Antibody | Human,Mouse | WB,IF,ELISA |
RAD23A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP019259HU | Recombinant Human UV excision repair protein RAD23 homolog A(RAD23A) | Yeast |
| CSB-BP019259HU CSB-MP019259HU |
Recombinant Human UV excision repair protein RAD23 homolog A(RAD23A) | Baculovirus Mammalian cell |
Recombinant Human Methylmalonyl-CoA mutase, mitochondrial(MMUT)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse ATP synthase subunit beta, mitochondrial(Atp5f1b),partial
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Rat Beta-nerve growth factor(Ngf)
Express system: Yeast
Species: Rattus norvegicus (Rat)
Recombinant Human E3 SUMO-protein ligase RanBP2(RANBP2),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Odontogenic ameloblast-associated protein(ODAM)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10(NDUFB10)
Express system: E.coli
Species: Homo sapiens (Human)
