Recombinant Human Uncharacterized protein C11orf20 (C11orf20)

Code CSB-YP873652HU
MSDS
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Source Yeast
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Code CSB-EP873652HU
MSDS
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Source E.coli
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Code CSB-EP873652HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP873652HU
MSDS
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Source Baculovirus
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Code CSB-MP873652HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CATSPERZ
Uniprot No.
Alternative Names
CATSPERZ; C11orf20; TEX40Cation channel sperm-associated protein subunit zeta; CatSper-zeta; CatSperzeta; Testis-expressed protein 40
Species
Homo sapiens (Human)
Expression Region
1-200
Target Protein Sequence
MEEKPSKVSL KSSDRQGSDE ESVHSDTRDL WTTTTLSQAQ LNMPLSEVCE GFDEEGRNIS KTRGWHSPGR GSLDEGYKAS HKPEELDEHA LVELELHRGS SMEINLGEKD TASQIEAEKS SSMSSLNIAK HMPHRAYWAE QQSRLPLPLM ELMENEALEI LTKALRSYQL GIGRDHFLTK ELQRYIEGLK KRRSKRLYVN
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel.
Gene References into Functions
  1. The frequency of the ESRRA/C11orf20 gene fusion in serous ovarian carcinomas of stages III and IV must be very low. PMID: 24504521
  2. ESRRA-C11orf20, a gene fusion between ESRRA and C11orf20 (TEX40) is recurrent serous ovarian carcinoma. PMID: 21949640
Subcellular Location
Cell projection, cilium, flagellum membrane; Peripheral membrane protein.
Database Links

HGNC: 19231

OMIM: 617511

KEGG: hsa:25858

STRING: 9606.ENSP00000330877

UniGene: Hs.97174

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