Recombinant Human YjeF N-terminal domain-containing protein 3 (YJEFN3)

Code CSB-BP026264HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-EP026264HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-MP026264HU
MSDS
Size Pls inquire
Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
YJEFN3
Uniprot No.
Alternative Names
YJEFN3; YjeF N-terminal domain-containing protein 3; YjeF_N3; hYjeF_N3
Species
Homo sapiens (Human)
Expression Region
1-299
Target Protein Sequence
MSSAAGPDPS EAPEERHFLR ALELQPPLAD MGRAELSSNA TTSLVQRRKQ AWGRQSWLEQ IWNAGPVCQS TAEAAALERE LLEDYRFGRQ QLVELCGHAS AVAVTKAFPL PALSRKQRTV LVVCGPEQNG AVGLVCARHL RVFEYEPTIF YPTRSLDLLH RDLTTQCEKM DIPFLSYLPT EVQLINEAYG LVVDAVLGPG VEPGEVGGPC TRALATLKLL SIPLVSLDIP SGWDAETGSD SEDGLRPDVL VSLAAPKRCA GRFSGRHHFV AGRFVPDDVR RKFALRLPGY TGTDCVAAL
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis.
Tissue Specificity
Expressed in theca cells in ovary and in Leydig cells in testis (at protein level). Also expressed in brain and mammary gland.
Database Links

HGNC: 24785

KEGG: hsa:374887

STRING: 9606.ENSP00000426964

UniGene: Hs.729508

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