Recombinant Human Zinc finger protein 282 (ZNF282)

Code CSB-YP026638HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP026638HU
MSDS
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Source E.coli
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Code CSB-EP026638HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP026638HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP026638HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ZNF282
Uniprot No.
Alternative Names
ZNF282; HUB1Zinc finger protein 282; HTLV-I U5RE-binding protein 1; HUB-1
Species
Homo sapiens (Human)
Expression Region
1-671
Target Protein Sequence
MQFVSTRPQP QQLGIQGLGL DSGSWSWAQA LPPEEVCHQE PALRGEMAEG MPPMQAQEWD MDARRPMPFQ FPPFPDRAPV FPDRMMREPQ LPTAEISLWT VVAAIQAVER KVDAQASQLL NLEGRTGTAE KKLADCEKTA VEFGNHMESK WAVLGTLLQE YGLLQRRLEN LENLLRNRNF WVLRLPPGSK GEAPKVPVTF VDIAVYFSED EWKNLDEWQK ELYNNLVKEN YKTLMSLDAE GSVPKPDAPV QAEPREEPCV WEQRHPEERE IPMDPEAGAE PLVPAQDASS QVKREDTLCV RGQRGLEERA IPTESITDSP ISAQDLLSRI KQEEHQCVWD QQDLADRDIP TDPNSESLIS AHDILSWIKQ EEQPYPWGPR DSMDGELGLD SGPSDSLLMV KNPPPAPPQP QPQPQPPQPQ LQSQPQPQSL PPIAVAENPG GPPSRGLLDD GFQVLPGERG SGEAPPGGDR STGGGGGDGG GGGGGAEAGT GAGGGCGSCC PGGLRRSLLL HGARSKPYSC PECGKSFGVR KSLIIHHRSH TKERPYECAE CEKSFNCHSG LIRHQMTHRG ERPYKCSECE KTYSRKEHLQ NHQRLHTGER PFQCALCGKS FIRKQNLLKH QRIHTGERPY TCGECGKSFR YKESLKDHLR VHSGGPGPGA PRQLPPPPER D
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression.
Gene References into Functions
  1. ZNF282 is E2F1 co-activator involved in esophageal squamous cell carcinoma PMID: 25373738
  2. SUMOylation of ZFP282 potentiates its positive effect on estrogen signaling in breast tumorigenesis. PMID: 22986521
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 13076

OMIM: 603397

KEGG: hsa:8427

STRING: 9606.ENSP00000262085

UniGene: Hs.729056

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