Purity
Greater than 90% as determined by SDS-PAGE.
Alternative Names
Dcn; Decorin; Bone proteoglycan II; PG-S2; PG40
Species
Mus musculus (Mouse)
Expression Region
35-354aa
Target Protein Sequence
GIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWDFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNQLKELPEKMPRTLQELRVHENEITKLRKSDFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRISDTNITAIPQGLPTSLTEVHLDGNKITKVDAPSLKGLINLSKLGLSFNSITVMENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYSAVSLYGNPVRYWEIFPNTFRCVYVRSAIQLGNYK
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
The expression region of this recombinant Mouse Dcn covers amino acids 35-354. The theoretical molecular weight of the Dcn protein is 51.9 kDa. This protein is generated in a e.coli-based system. The Dcn gene fragment has been modified by fusing the N-terminal 6xHis-SUMO tag, providing convenience in detecting and purifying the recombinant Dcn protein during the following stages.
Decorin (Dcn) in mice is a proteoglycan primarily found in the extracellular matrix (ECM) of connective tissues. It plays a crucial role in regulating collagen fibrillogenesis and maintaining tissue structure. Decorin binds to collagen fibers, influencing their organization and providing mechanical strength to tissues. Beyond its structural functions, decorin also modulates cellular processes, including cell adhesion, proliferation, and migration. Its ability to interact with growth factors and receptors makes decorin a key player in tissue homeostasis, wound healing, and inflammation. Research areas involving decorin often explore its implications in tissue development, musculoskeletal disorders, cancer progression, and therapeutic applications aimed at manipulating ECM dynamics for tissue repair and regeneration.