Recombinant Mouse Interleukin-20(Il20)

Code CSB-YP872875MO
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Source Yeast
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Code CSB-EP872875MO
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Source E.coli
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Code CSB-EP872875MO-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP872875MO
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Source Baculovirus
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Code CSB-MP872875MO
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names Il20
Uniprot No. Q9JKV9
Alternative Names Il20; Zcyto10Interleukin-20; IL-20; Cytokine Zcyto10
Species Mus musculus (Mouse)
Expression Region 25-176
Target Protein Sequence LKTLHL GSCVITANLQ AIQKEFSEIR DSVQAEDTNI DIRILRTTES LKDIKSLDRC CFLRHLVRFY LDRVFKVYQT PDHHTLRKIS SLANSFLIIK KDLSVCHSHM ACHCGEEAME KYNQILSHFI ELELQAAVVK ALGELGILLR WMEEML
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Function
Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.
Gene References into Functions
  1. The authors conclude that IL-20 affects bone formation and downregulates osteoblastogenesis by modulating sclerostin, osterix, RUNX2, and osteoprotegerin on osteoblasts. PMID: 27075747
  2. Data show that interleukin 20 (IL-20) is expressed in type 2 diabetic db/db islets and contributes to inflammation. PMID: 26162095
  3. IL-20 is primarily up regulated in psoriatic skin at the post-transcriptional level. PMID: 26176762
  4. our results suggest that IL-20 plays pivotal roles in the tumor progression of breast cancer. IL-20 expression in breast cancer tissue is associated with a poor clinical outcome. PMID: 22238453
  5. IL-20 is a proatherogenic cytokine that contributes to the progression of atherosclerosis. PMID: 16778121
  6. IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs PMID: 17878297
  7. novel effects of IL-20 on mesangial cells and its association with lupus nephritis. PMID: 18771958

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Subcellular Location Secreted.
Protein Families IL-10 family
Database Links

KEGG: mmu:58181

STRING: 10090.ENSMUSP00000027673

UniGene: Mm.103794

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Address
7505 Fannin St Ste 610-322 Houston, TX 77054, USA
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