Recombinant Mouse Interleukin-20 (Il20)

Code CSB-YP872875MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP872875MO
MSDS
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Source E.coli
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Code CSB-EP872875MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP872875MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP872875MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Il20
Uniprot No.
Alternative Names
Il20; Zcyto10Interleukin-20; IL-20; Cytokine Zcyto10
Species
Mus musculus (Mouse)
Expression Region
25-176
Target Protein Sequence
LKTLHL GSCVITANLQ AIQKEFSEIR DSVQAEDTNI DIRILRTTES LKDIKSLDRC CFLRHLVRFY LDRVFKVYQT PDHHTLRKIS SLANSFLIIK KDLSVCHSHM ACHCGEEAME KYNQILSHFI ELELQAAVVK ALGELGILLR WMEEML
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.
Gene References into Functions
  1. The authors conclude that IL-20 affects bone formation and downregulates osteoblastogenesis by modulating sclerostin, osterix, RUNX2, and osteoprotegerin on osteoblasts. PMID: 27075747
  2. Data show that interleukin 20 (IL-20) is expressed in type 2 diabetic db/db islets and contributes to inflammation. PMID: 26162095
  3. IL-20 is primarily up regulated in psoriatic skin at the post-transcriptional level. PMID: 26176762
  4. our results suggest that IL-20 plays pivotal roles in the tumor progression of breast cancer. IL-20 expression in breast cancer tissue is associated with a poor clinical outcome. PMID: 22238453
  5. IL-20 is a proatherogenic cytokine that contributes to the progression of atherosclerosis. PMID: 16778121
  6. IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs PMID: 17878297
  7. novel effects of IL-20 on mesangial cells and its association with lupus nephritis. PMID: 18771958

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Subcellular Location
Secreted.
Protein Families
IL-10 family
Database Links
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