Recombinant Mouse Prickle-like protein 2 (Prickle2), partial

Code CSB-YP800362MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP800362MO
MSDS
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Source E.coli
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Code CSB-EP800362MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP800362MO
MSDS
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Source Baculovirus
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Code CSB-MP800362MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Prickle2
Uniprot No.
Alternative Names
Prickle2; Prickle-like protein 2
Species
Mus musculus (Mouse)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. The results of this study demonstrated that Prickle2 is required for normal ependymal motile cilia development and function. PMID: 24708399
  2. Prickle2 disruption causes behavioral abnormalities like altered social interaction, learning abnormalities and behavioral inflexibility. In mouse hippocampal neurons, it reduced dendrite branching, synapse number and postsynaptic density size. PMID: 23711981
  3. The cell polarity phenotype was efficiently rescued by nuclear but not cytoplasmic Prickle2, demonstrating the nuclear localization of Prickle2 is critical for its function. PMID: 22333836
  4. The prickle2 protein is a novel PSD protein that interacts with PSD-95 and NMDA receptors through complex formations in the brain. PMID: 21324980
  5. Putative planar cell polarity protein prickle-like 2 is distributed in crescents on the medial sides of vestibular epithelial cells before the morphological polarization of hair cells. PMID: 17376975

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Subcellular Location
Nucleus membrane.
Protein Families
Prickle / espinas / testin family
Tissue Specificity
Expressed in the hippocampus and cerebral cortex.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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