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Recombinant Mouse Sushi domain-containing protein 4 (Susd4), partial

Recombinant Mouse Sushi domain-containing protein 4 (Susd4), partial

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Code	CSB-EP805887MOa0
Abbreviation	Recombinant Mouse Susd4 protein, partial
MSDS	MSDS Datasheet
Size	$388
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Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details
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Target Background

Product Details

Purity

Greater than 85% as determined by SDS-PAGE.

Target Names

Susd4

Uniprot No.

Q8BH32

Research Area

Cell Biology

Alternative Names

Susd4; Sushi domain-containing protein 4

Species

Mus musculus (Mouse)

Source

E.coli

Expression Region

42-319aa

Target Protein Sequence

FGPAQLTGGFDDLNVCADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKHFNGTLGWVPSDKPVCIQEDCRIPQIEDAEIRNKTYRHGEKLVIDCHEGFKIRYPDLYNLVSLCRDDGTWDNLPICQGCLRPLASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRCLALEVCPLPPMVSHGDFICHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Mol. Weight

35.5 kDa

Protein Length

Partial

Tag Info

N-terminal 6xHis-tagged

Form

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

The Recombinant Mouse Susd4, a meticulously engineered protein that is set to be a valuable asset in your Cell Biology research. Sourced from Mouse species, this recombinant protein is the precise representation of the Sushi domain-containing protein 4. With its production from the E.coli system, the Recombinant Mouse Susd4 assures uncompromised reliability and precision for your experiments.

The Recombinant Mouse Susd4 expresses a partial length of the protein, encompassing the amino acid sequence from the 42nd to the 319th position. This construct features an N-terminal 6xHis tag for easy protein purification and detection. The purity of the protein is affirmed to be greater than 85%, as validated by SDS-PAGE. The Recombinant Mouse Susd4 is available in both liquid and lyophilized powder forms, enabling you to choose the most suitable format for your research needs.

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Target Background

Function

Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.

Gene References into Functions

analysis of cloning, expression, refolding, and tissue distribution of Sushi domain-containing protein 4 PMID: 20348246

Subcellular Location

Membrane; Single-pass type I membrane protein.

Tissue Specificity

High expression in brain and eye, with weaker expression in spinal cord and testis. Detected in white matter of brain and in the outer segments of photoreceptors.

Database Links

KEGG: mmu:96935

STRING: 10090.ENSMUSP00000082873

UniGene: Mm.331052

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