Product Details

Purity

Greater than 85% as determined by SDS-PAGE.

Activity

Not Test

Target Names

Cspg5

Uniprot No.

Q9ERQ6

Research Area

Others

Alternative Names

Acidic leucine-rich EGF-like domain-containing brain protein;Neuroglycan C

Species

Rattus norvegicus (Rat)

Source

E.coli

Expression Region

31-428aa

Target Protein Sequence

VPAREAGSAIEAEELVRSGLAWESRANDTREEAGLPAAGEDETSWTERGSELAAVGPGVGPEETLEASAAVTGTAWLEADGTGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATEASGPPSPTLRDKPSLVPELPKEIPLEVWLNLGGSTPDPQRPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGTDMGRFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEEDKDAVGGGDLEDESDLLLPSQKPGVGPGTGQPTSRWHAVPPQHTLGMVPGGSISLRPRPGDPGKDLATSENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Mol. Weight

47.3 kDa

Protein Length

Partial

Tag Info

N-terminal 10xHis-tagged and C-terminal Myc-tagged

Form

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Target Background

Function

May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.

Gene References into Functions

Rac1, Cdc42, and RhoG perform very specific and non-redundant functions at different levels of hierarchy in regulating dendritic tree complexity induced by CALEB/NGC PMID: 27412363
there is a glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C PMID: 15331613
neuroglycan C is a novel component of midkine receptors involved in process elongation PMID: 16901907
PI3K-Akt-mammalian target of rapamycin (mTOR) signaling pathway and PKC are important for CALEB/NGC-induced stimulation of dendritic branching. CALEB/NGC-induced spine morphogenesis is independent of PI3K but depends on PKC. PMID: 17431398

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, synaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cell surface.

Tissue Specificity

Expressed in cerebral cortex and cerebellum. Expressed in retina (at protein level).

Database Links

KEGG: rno:50568

STRING: 10116.ENSRNOP00000028278

UniGene: Rn.10146

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Code	CSB-EP866833RA
Abbreviation	Recombinant Rat Cspg5 protein, partial
MSDS	MSDS Datasheet
Size	$256
	Order now
Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Have Questions?	Leave a Message or Start an on-line Chat

Recombinant Rat Chondroitin sulfate proteoglycan 5 (Cspg5), partial

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