Recombinant Rat Interleukin-34 (Il34)

Code CSB-YP679693RA
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP679693RA
MSDS
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Source E.coli
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Code CSB-EP679693RA-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP679693RA
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP679693RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Il34
Uniprot No.
Alternative Names
Il34Interleukin-34; IL-34
Species
Rattus norvegicus (Rat)
Expression Region
21-234
Target Protein Sequence
NENLEIWTLA QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL KAHVSERELR YLWVLVSLNA TESVLDVLLE GHPSWKYLQE VQTLLENVQR SLMDVEIGPH VEAVLSLLST PGLSLKLVRP KALLDNCFRV MELLYCSCCK QSPILKWQDC ELPRLHPHSP ESLMQCAATN VYPLPRQPPT SLPRSPSSNH GPLP
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Gene References into Functions
  1. In a rat cardiac allograft model, IL-34 induced transplant tolerance associated with a total inhibition of alloantibody production. Treatment of rats with IL-34 promoted allograft tolerance mediated by induction of CD8+ and CD4+ Tregs. PMID: 26389674
Subcellular Location
Secreted.
Protein Families
IL-34 family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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