Code | CSB-RA180423A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
DDX6 is a conserved DEAD-box protein (DBP) that plays central roles in cytoplasmic RNA regulation, including processing body (P-body) assembly, mRNA decapping, and translational repression. DDX6 has pro- and antiviral roles in viral infections. DDX6 modulates replication and the stability of HCV RNA through interaction with miR-122 and the viral-5′UTR. In mosquitoes, DDX6 plays a role against the flavivirus, such as West Nile virus and Zika virus. In HIV, DDX6 is implicated in negatively regulating viral replication.
The production of this recombinant DDX6 antibody was carried out in vitro. It began with immunization of animals so that the B cells could be obtained. The next step was selection of B cells. The positive cells would be screened out for the next step, single B cell antibody sequencing and cloning. Once the DDX6 antibody sequence was obtained, it would be inserted into a plasmid, which could be transfected into mammalian cells for the expression of DDX6 antibody.There are currently no reviews for this product.