Code | CSB-RA271553A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
DMD is a large cytoskeletal protein that's present on the inside of muscle fibers. DMD, which is found in numerous tissues throughout the body, plays a crucial function in muscle contraction by maintaining the muscle membrane. DMDbinds to a variety of proteins and glycoproteins in skeletal muscle to create the dystrophin-glycoprotein complex (DGC), a key structural unit in skeletal muscle that connects a muscle fiber's cytoskeleton (f-actin) to the extracellular matrix (ECM). DMD deficiency or absence causes two illnesses that result in gradual muscle degeneration. Dystrophin deficiency compromises the sarcolemmal membrane's integrity, making it vulnerable to mechanical damage, leading to Duchenne muscular dystrophy (DMD).
The production of this recombinant DMD antibody started with identifying and cloning the genes for antibody expression. After the DMD antibody was cloned into an expression plasmid, the plasmid could be introduced into the mammalian cell to produce the target recombinant antibody. This recombinant DMD antibody has been validated in ELISA, IHC.There are currently no reviews for this product.