Code | CSB-RA568544A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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FC | 1:50-1:200 |
To create the ENTPD1 recombinant monoclonal antibody, a multistep process is followed. The ENTPD1 monoclonal antibody is first harvested, and its gene sequence is determined. A vector carrying the ENTPD1 monoclonal antibody gene is then constructed and transfected into a host cell line for culture. During ENTPD1 monoclonal antibody synthesis, a synthesized peptide from human ENTPD1 is used as an immunogen. The ENTPD1 recombinant monoclonal antibody is then purified via affinity chromatography, and its specificity is examined using ELISA and FC applications. It only recognizes human ENTPD1 protein.
ENTPD1, also known as CD39, is a protein that plays a key role in purinergic signaling, which is a process that regulates a wide range of cellular functions, including neurotransmission, immune response, and inflammation. Specifically, CD39 is an ectonucleoside triphosphate diphosphohydrolase that catalyzes the hydrolysis of extracellular ATP and ADP to AMP, which can then be further hydrolyzed to adenosine by other enzymes. This conversion of ATP and ADP to adenosine is important for regulating the balance between pro-inflammatory and anti-inflammatory responses in the immune system. CD39 is expressed on the surface of various cell types, including immune cells such as T cells and B cells, and is involved in a range of physiological processes, including regulation of blood clotting, insulin secretion, and vascular function.
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