Code | CSB-RA246102A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
IP | 1:200-1:1000 |
FOXA1, also known as HNF-3α, is a pioneering androgen receptor (AR) transcription factor that is essential for prostate lineage-specific gene expression. It is important for the differentiation and development of epithelial cells in a variety of organs, including the pancreatic, prostate, and breast. The expression of the FOXA1 protein was shown to be higher in breast cancer cells as the estrogen/androgen receptors were activated. FOXA1 has been demonstrated to suppress epithelial-to-mesenchymal transition (EMT) in pancreatic cancer cells, indicating that it is a pro-differentiation factor.
The production of this recombinant FOXA1 antibody started with identifying and cloning the genes for antibody expression. After the FOXA1 antibody was cloned into an expression plasmid, the plasmid could be introduced into the mammalian cell to produce the target recombinant antibody. This recombinant FOXA1 antibody has been validated in ELISA, WB, IHC, IP.There are currently no reviews for this product.