H2BC12 Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA287439A0HU
Size	US$210
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Image	Immunocytochemical staining of HepG2 cells with Histone H2B antibody. Nuclei were stained blue with DAPI; Histone H2B was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm. Western blotting analysis using Histone H2B antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with Histone H2B antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O60814

Target Names

H2BC12

Alternative Names

H2BC12; H2B Clustered Histone 12; HIST1H2B; H2BFAiii; H2BFT; Histone Cluster 1 H2B Family Member K; H2B Histone Family, Member T; HIRA-Interacting Protein 1; Histone Cluster 1, H2bk; Histone H2B Type 1-K; Histone 1, H2bk; H2B K; Histone Family Member; HIRIP1; H2B/S; H2BK

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human H2BC12 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

Rabbit IgG

Clone No.

18H6

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Form

Liquid

Tested Applications

ELISA, WB, ICC

Recommended Dilution

Application	Recommended Dilution
WB	1:4000-1:20000
ICC	1:100-1:1000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Gene References into Functions

Histone H2B antimicrobial peptides exhibit antibacterial activity and contribute to the formation of the antimicrobial barrier of the colonic epithelium PMID: 15019208

Subcellular Location

Nucleus. Chromosome.

Protein Families

Histone H2B family

Database Links

HGNC: 13954

OMIM: 615045

KEGG: hsa:85236

STRING: 9606.ENSP00000349430

UniGene: Hs.437275

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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