Code | CSB-RA937491A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
IHC | 1:50-1:200 |
FC | 1:50-1:200 |
The ISG15 recombinant monoclonal antibody is generated using genetic engineering techniques that involve the cloning and expression of the gene that encodes for the ISG15 monoclonal antibody. The immunogen used for this process is a synthesized peptide that is derived from the human ISG15 protein. The obtained ISG15 recombinant monoclonal antibody is purified using affinity chromatography to ensure high purity. This ISG15 recombinant monoclonal antibody specifically recognizes and binds to the ISG15 protein and has been validated for use in human samples. Three applications including ELISA, IHC, and FC have been carried out to test the quality and specificity of the ISG15 recombinant monoclonal antibody.
ISG15 is a small protein that is induced in response to type I interferons, viral infections, and other stress signals. Its main function is as a ubiquitin-like modifier, which means it covalently attaches to target proteins in a process called ISGylation. This modification can alter the function of target proteins, such as promoting their degradation or altering their activity. ISG15 is also involved in immune regulation and can activate the immune system's response to viral infections by promoting the maturation and activation of dendritic cells and natural killer cells. Additionally, it has been shown to play a role in regulating inflammation, apoptosis, and DNA damage responses.
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