Code | CSB-RA921474A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The NPC1L1 recombinant monoclonal antibody is a highly specific antibody that recognizes the human protein NPC1L1. This NPC1L1 antibody was made by transfecting human NPC1L1 monoclonal antibody gene-vector clones into a cell line for in vitro expression, then purifying the antibody using affinity chromatography from the tissue culture supernatant (TCS). The human NPC1L1 monoclonal antibody was produced by immunizing mice with a human NPC1L1 synthetic peptide. The isotype of this NPC1L1 antibody is the same as rabbit IgG. Recommended applications for this NPC1L1 antibody are ELISA and IHC.
NPC1L1 is a multi-transmembrane protein that is involved in both dietary and biliary cholesterol absorption. It also aids in the maintenance of intestinal cholesterol homeostasis. The cholesterol absorption inhibitor class of drugs, of which ezetimibe is the first extensively used one, has identified NPC1L1 as the molecular target.
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