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| Code | CSB-RA906015A0HU |
| Size | US$210 |
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| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:5000 |
The NUDC antibody CSB-RA906015A0HU is a rabbit IgG recombinant monoclonal antibody. The acquisition of the HUAC6 monoclonal antibody using the synthesized peptide derived from the human NUDC immunizes animals, the determination of the NUDC monoclonal antibody's DNA sequence, and the cloning of the DNA sequence into the plasmid and subsequent transfection into cell lines for expression are among the procedures used in its production. Affinity chromatography was used to purify this NUDC antibody. It has been put to the test in a variety of ways, including ELISA and WB. The NUDC protein from human, mouse, and rat samples reacts with this NUDC antibody.
NUDC, a dynein-associated nuclear movement protein, forms a biochemical complex with dynein/dynactin complex components and is involved in nuclear translocation in proliferating neural progenitors and migrating neurons in culture. NUDC regulates microtubule structure at the midzone and midbody, which is important for mitosis and cytokinesis. By stabilizing cofilin 1 in an Hsp90-independent manner, NUDC modulates actin dynamics and cell motility.
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