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| Code | CSB-RA213218A0HU |
| Size | US$210 |
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| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:5000 |
| IF | 1:20-1:200 |
In yeast, fly, and mammalian cells, PCYT1A, the rate-limiting enzyme of phosphatidylcholine (PC) synthesis, is intranuclear and re-locates to the nuclear membrane in response to the demand for membrane PL production. Membrane lipid stored curvature elastic (SCE) stress is increased by PC deficiency. PCYT1A deletions caused functional impairment in cells that generate PC for secretion as well as membrane maintenance. Lipodystrophy, spondylometaphyseal dysplasia with cone-rod dystrophy (SMD-CRD), and isolated retinal dystrophy are all caused by mutations in the PCYT1A gene.
The preparation of the recombinant PCYT1A antibody involves the mammalian cell lines expression of plasma vectors containing PCYT1A antibody genes. B cells isolated from immunized animals' blood were treated to obtain RNA, which underwent reverse transcription to yield DNA genes. Antibody genes were sequenced and screened from the DNA. After transient expression, cell supernatant was collected and then purified using Affinity-chromatography to obtain the recombinant PCYT1A antibody. This recombinant PCYT1A antibody is recommended to use in the PCYT1A for the detection of PCYT1A protein from Human.There are currently no reviews for this product.
