Code | CSB-RA984883A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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FC | 1:50-1:200 |
The process of producing the PTX3 recombinant monoclonal antibody is complex and involves multiple steps. The first step is to harvest the PTX3 monoclonal antibody and sequence its gene. The PTX3 monoclonal antibody gene is inserted into a plasmid vector and then introduced into a host cell line for culture. During PTX3 monoclonal antibody production, a synthesized peptide from human PTX3 acts as the immunogen. Affinity chromatography is used to purify the PTX3 recombinant monoclonal antibody, which is then evaluated for specificity through ELISA and FC applications. The PTX3 recombinant monoclonal antibody only shows reactivity with human PTX3 protein.
Pentraxin 3 (PTX3) is a multifunctional glycoprotein and an essential component of the humoral arm of the innate immune system. It plays a crucial role in host defense by recognizing and binding to a range of microorganisms, including bacteria, fungi, and viruses, and triggering an inflammatory response to eliminate them. PTX3 also functions as a modulator of inflammation, angiogenesis, and tissue repair by interacting with various molecules, including complement components, growth factors, extracellular matrix proteins, and immune cells. Additionally, PTX3 has been implicated in several pathological conditions, such as infections, cardiovascular diseases, and cancer, and serves as a potential diagnostic and prognostic biomarker.
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