Code | CSB-RA810267A0HU |
Size | US$210 |
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The recombinant RIOX2 antibody is a monoclonal antibody made in vitro using the RIOX2 antibody genes that are typically expressed from a plasmid in a stable mammalian cell line. The genes coding for the RIOX2 antibody will ultimately assemble into a fully functional antibody after translation. The synthesized antibody is the recombinant antibody against RIOX2. It underwent purification using affinity-chromatography. This recombinant RIOX2 antibody is suitable for use in the ELISA to detect the RIOX2 protein from Human.
RIOX2, a JmjC (Jumonji-C) domain-containing 2-oxoglutarate (2OG)-dependent oxygenase, is implicated in gene transcription in eukaryotic cells. It promotes cell proliferation, cycle transition, and anti-apoptosis carcinogenic activities. RIOX2 upregulation has been found in several human solid and hematological malignancies, including colon, esophagus, lung, lymphocyte, kidney, nervous system, liver, breast, pancreas, and gastric cancers. Enhanced RIOX2 expression has been associated with a poor prognosis, and evidence has shown that RIOX2 downregulation inhibits cancer cell growth and survival.
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