Code | CSB-RA581950A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
RPTOR, also called RAPTOR, an essential component of mTORC1, functions as a scaffold for mTOR kinase to recruit and phosphorylate specific substrates such as S6K1 and to initiate the nucleic acid synthesis and cap-dependent translation as well as SREBP1 to promote cell metabolism. It is essential for mTORC1 activity and critical for the regulation of mTORC1 activity in response to insulin signaling and nutrient and energy sufficiency. RAPTOR also plays an instructive role in the development and function of B cells, and the deficiency of RAPTOR impairs the survival and proliferation of pre-B cells.
The recombinant RPTOR antibody was produced by cloning antibody genes into an expression vectors, which were subsequently introduced into mammalian cells to provide animal-free antibody production. This RPTOR antibody has been validated in ELISA, IHC. It has the features of improved affinity, stability, and consistency between different batches.There are currently no reviews for this product.