Recombinant Bovine Leukotriene B4 receptor 1 (LTB4R)

Code CSB-CF660996BO
MSDS
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
LTB4R
Uniprot No.
Alternative Names
LTB4R; Leukotriene B4 receptor 1; LTB4-R 1; LTB4-R1
Species
Bos taurus (Bovine)
Expression Region
1-349
Target Protein Sequence
MNTTSPAAPSSSGVSFISLLVIIVLSVALAVGLPGNSFVVWSILAKLRKRSVTALMVLHL ALADLAVLLTAPFFLYSVAQGTWTFGLSSCRLFHYVCGVSMYASVLLIMTMSLDRSLAVA LPFVSQKLRTKAVAWRVLAGIWVMSVLLATPVLLYRTVHLGLNNRSLTCFLKYPSERHRA FHLFFEVITGFLLPFLVVVASYCDIGRRLRARRFRRSRRTGRLVALIILAFAAFWLPYHV VNLAEGFRAAAGKALGSGPVGRRLLLARHVLITLAFLSSSVNPLLYACAGGGLLRSAGVG FIAKLLEGTGSETSSSRRKGTLAQTLRGTPASPEPDPAESLTASTNPLE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Gene References into Functions
  1. In luteal-phase endometrium, expression of 5-LO (5-lipoxygenase) and LTB4R (leukotriene B4 receptor) is highest on Days 2-4; expression of LTCS (leukotriene-C4 synthase) and CysLTR2 (cysteinyl leukotriene receptor 2) is highest on Days 16-18. In luteal-phase endometrium, LTB4 level is highest on Days 2-4; LTC4 level is highest on Days 16-18. Studies were conducted in Poland on Holstein Polish Black and White dairy cows. PMID: 25483008
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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