Recombinant Chicken Tumor necrosis factor receptor superfamily member 16(NGFR)

Code CSB-CF015780CH
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names NGFR
Uniprot No. P18519
Alternative Names NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD
Species Gallus gallus (Chicken)
Expression Region 20-416
Target Protein Sequence SKEKCLTKMYTTSGECCKACNLGEGVVQPCGVNQTVCEPCLDSVTYSDTVSATEPCKPCTQCVGLHSMSAPCVESDDAVCRCAYGYFQDELSGSCKECSICEVGFGLMFPCRDSQDTVCEECPEGTFSDEANFVDPCLPCTICEENEVMVKECTATSDAECRDLHPRWTTHTPSLAGSDSPEPITRDPFNTEGMATTLADIVTTVMGSSQPVVSRGTADNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANNRPVNQTPSPEGEKLHSDSGISVDSQSLHDQQPPNQSTQGPAPKGDGSLYASLPPSKQEEVEKLLSSSAEETWRQLAGELGYKEDLIDCFTREESPARALLADWSAKETATLDALLVALRKIQRGDIAESLYSESTATSPV
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Function
Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Necessary for the circadian oscillation of clock genes in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Cell projection, dendritic spine.
Tissue Specificity Detected in embryonic dorsal root ganglion and retina.
Database Links

STRING: 9031.ENSGALP00000020402

UniGene: Gga.39799

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