Recombinant Human 3-keto-steroid reductase(HSD17B7)

Code CSB-CF010776HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P56937
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names HSD17B7
Protein Names Recommended name: 3-keto-steroid reductase EC= Alternative name(s): 17-beta-hydroxysteroid dehydrogenase 7 Short name= 17-beta-HSD 7 Estradiol 17-beta-dehydrogenase 7 EC=
Expression Region 1-341
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Responsible for the reduction of the keto group on the C-3 of sterols.
Subcellular Location Cell membrane, Single-pass membrane protein
Protein Families Short-chain dehydrogenases/reductases (SDR) family, ERG27 subfamily
Tissue Specificity Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is e
Database Links

HGNC: 5215

OMIM: 606756

KEGG: hsa:51478

STRING: 9606.ENSP00000254521

UniGene: Hs.492925

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