Recombinant Human Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(MGAT1)

Code CSB-CF013773HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P26572
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MLKKQSAGLVLWGAILFVAWNALLLLFFWTRPAPGRPPSVSALDGDPASLTREVIRLAQDAEVELERQRGLLQQIGDALSSQRGRVPTAAPPAQPRVPVTPAPAVIPILVIACDRSTVRRCLDKLLHYRPSAELFPIIVSQDCGHEETAQAIASYGSAVTHIRQPDLSSIAVPPDHRKFQGYYKIARHYRWALGQVFRQFRFPAAVVVEDDLEVAPDFFEYFRATYPLLKADPSLWCVSAWNDNGKEQMVDASRPELLYRTDFFPGLGWLLLAELWAELEPKWPKAFWDDWMRRPEQRQGRACIRPEISRTMTFGRKGVSHGQFFDQHLKFIKLNQQFVHFTQLDLSYLQREAYDRDFLARVYGAPQLQVEKVRTNDRKELGEVRVQYTGRDSFKAFAKALGVMDDLKSGVPRAGYRGIVTFQFRGRRVHLAPPLTWEGYDPSWN
Source in vitro E.coli expression system
Gene Names MGAT1
Protein Names Recommended name: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase EC= 2.4.1.101Alternative name(s): N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I Short name= GNT-I Short name= GlcNAc-T I
Expression Region 1-445
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 13 family
Tissue Specificity Appears to be present in all tissues.
Database Links

HGNC: 7044

OMIM: 160995

KEGG: hsa:4245

STRING: 9606.ENSP00000311888

UniGene: Hs.519818

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