Recombinant Human Erlin-1(ERLIN1)

Code CSB-CF007790HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O75477
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names ERLIN1
Protein Names Recommended name: Erlin-1 Alternative name(s): Endoplasmic reticulum lipid raft-associated protein 1 Protein KE04 Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 Short name= SPFH domain-containing protein 1
Expression Region 1-346
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex
Involvement in disease Spastic paraplegia 62, autosomal recessive (SPG62)
Subcellular Location Endoplasmic reticulum membrane, Single-pass type II membrane protein
Protein Families Band 7/mec-2 family
Tissue Specificity Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine.
Database Links

HGNC: 16947

OMIM: 611604

KEGG: hsa:10613

STRING: 9606.ENSP00000384900

UniGene: Hs.150087

Related Products

ERLIN1 Antibodies

ERLIN1 Antibodies for Homo sapiens (Human)

ERLIN1 Antibodies for Human

ERLIN1 Proteins

ERLIN1 Proteins for Homo sapiens (Human)

Most popular with customers


Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 CUSABIO TECHNOLOGY LLC All Rights Reserved.