Recombinant Human Gamma-aminobutyric acid receptor subunit alpha-4(GABRA4)

Code CSB-CF009143HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P48169
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names GABRA4
Protein Names Recommended name: Gamma-aminobutyric acid receptor subunit alpha-4Alternative name(s): GABA(A) receptor subunit alpha-4
Expression Region 36-554
Tag Info 10xHis-SUMO-tag
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein
Protein Families Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA4 sub-subfamily
Database Links

HGNC: 4078

OMIM: 137141

KEGG: hsa:2557

STRING: 9606.ENSP00000264318

UniGene: Hs.248112

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