Recombinant Human Gamma-glutamyltranspeptidase 2(GGT2)

Code CSB-CF009395HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P36268
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAMAADAKQCLEIGRDTLRDGGSAVDAAIAALLCVGLMNAHSMGIGVGLFLTIYNSTTGKAEVINAREVAPRLAFASMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAVLENKRTVIEQQPVLWYVFCRDRKVLREGERLTLPRLADTYEMLAIEGAQAFYNGSLMAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSARLSGPVLALILNILKGYNFSRESVETPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRSQISDHTTHPISYYKPEFYTPDDGG
Source in vitro E.coli expression system
Gene Names GGT2
Protein Names Recommended name: Gamma-glutamyltranspeptidase 2 Short name= GGT 2 EC= 2.3.2.2Alternative name(s): Gamma-glutamyltransferase 2 Glutathione hydrolase 2 EC= 3.4.19.13Cleaved into the following 2 chains: 1. Gamma-glutamyltranspeptidase 2 heavy chai
Expression Region 1-380
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Isoform 1, isoform 2 and isoform 3 lack catalytic activity due to its inability to undergo the autocatalytic cleavage needed to produce a mature, enzymatically active heterodimer.
Subcellular Location Cytoplasm, perinuclear region, Endoplasmic reticulum
Protein Families Gamma-glutamyltransferase family
Tissue Specificity Highly expressed in fetal and adult kidney and liver.
Database Links

HGNC: 4251

OMIM: 137181

STRING: 9606.ENSP00000385721

UniGene: Hs.568255

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