Recombinant Human Killer cell immunoglobulin-like receptor 2DL1(KIR2DL1)

Code CSB-CF012352HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P43626
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names KIR2DL1
Protein Names Recommended name: Killer cell immunoglobulin-like receptor 2DL1 Alternative name(s): CD158 antigen-like family member A MHC class I NK cell receptor Natural killer-associated transcript 1 Short name= NKAT-1 p58 natural killer cell receptor cl
Expression Region 22-348
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
Subcellular Location Cell membrane, Single-pass type I membrane protein
Protein Families Immunoglobulin superfamily
Tissue Specificity Expressed by NK cells.
Database Links

HGNC: 6329

OMIM: 604936

KEGG: hsa:3802

STRING: 9606.ENSP00000336769

UniGene: Hs.654605

Pathway Cellular senescence
Antigen processing and presentation
Natural killer cell mediated cytotoxicity

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