Recombinant Human Long-chain-fatty-acid--CoA ligase 1(ACSL1)

Code CSB-CF001191HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P33121
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names ACSL1
Protein Names Recommended name: Long-chain-fatty-acid--CoA ligase 1 EC= Alternative name(s): Acyl-CoA synthetase 1 Short name= ACS1 Long-chain acyl-CoA synthetase 1 Short name= LACS 1 Long-chain acyl-CoA synthetase 2 Short name= LACS 2 Lon
Expression Region 1-698
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
Subcellular Location Mitochondrion outer membrane, Single-pass type III membrane protein, Peroxisome membrane, Single-pass type III membrane protein, Microsome membrane, Single-pass type III membrane protein, Endoplasmic reticulum membrane, Single-pass type III membrane protein
Protein Families ATP-dependent AMP-binding enzyme family
Tissue Specificity Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.
Database Links

HGNC: 3569

OMIM: 152425

KEGG: hsa:2180

STRING: 9606.ENSP00000281455

UniGene: Hs.406678

Pathway PPAR signaling pathway
Adipocytokine signaling pathway

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