ACSL1

ACSF 1, long-chain acyl-CoA synthetase 1, is a key enzyme in lipid metabolism, present in diverse biological tissues. It catalyzes the union of long-chain fatty acids with CoA to produce fatty acyl-CoA, marking the initial step in fatty acid β-oxidation and a pivotal moment in triglyceride synthesis. ACSF 1 is instrumental in the regulation of lipid balance, energy metabolism, and cellular signaling. Abnormalities in its expression are correlated with a host of diseases, including neurodegenerative conditions, cardiovascular diseases, and metabolic syndrome, highlighting its broad research potential in biomedicine. ACSF 1 stands as a central figure in basic metabolism studies and a promising target for therapeutic interventions.