Recombinant Human Macrophage scavenger receptor types I and II(MSR1)

Code CSB-CF015050HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P21757
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLVFAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSNMEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSLISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL
Source in vitro E.coli expression system
Gene Names MSR1
Protein Names Recommended name: Macrophage scavenger receptor types I and II Alternative name(s): Macrophage acetylated LDL receptor I and II Scavenger receptor class A member 1 CD_antigen= CD204
Expression Region 1-451
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL)
Involvement in disease Prostate cancer (PC); Barrett esophagus (BE)
Subcellular Location Membrane, Single-pass type II membrane protein
Tissue Specificity Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain.
Database Links

HGNC: 7376

OMIM: 153622

KEGG: hsa:4481

STRING: 9606.ENSP00000262101

UniGene: Hs.147635

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