Recombinant Rat Long-chain-fatty-acid--CoA ligase 6(Acsl6)

Code CSB-CF001195RA
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P33124
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Rattus norvegicus (Rat)
Source in vitro E.coli expression system
Gene Names Acsl6
Protein Names Recommended name: Long-chain-fatty-acid--CoA ligase 6 EC= Alternative name(s): Long-chain acyl-CoA synthetase 6 Short name= LACS 6 Long-chain-fatty-acid--CoA ligase, brain isozyme
Expression Region 1-697
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Subcellular Location Mitochondrion outer membrane, Single-pass type III membrane protein, Peroxisome membrane, Single-pass type III membrane protein, Microsome membrane, Single-pass type III membrane protein, Endoplasmic reticulum membrane, Single-pass type III membrane protein
Protein Families ATP-dependent AMP-binding enzyme family
Tissue Specificity Expressed predominantly in brain and, to a much lesser extent, in heart and adrenal.
Database Links

KEGG: rno:117243

STRING: 10116.ENSRNOP00000055608

UniGene: Rn.33697

Pathway PPAR signaling pathway
Adipocytokine signaling pathway

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