Recombinant Rat T-cell surface glycoprotein CD8 alpha chain(Cd8a)

Code CSB-CF004966RA
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names Cd8a
Uniprot No. P07725
Alternative Names Cd8aT-cell surface glycoprotein CD8 alpha chain; CD8 antigen 32 kDa chain; OX-8 membrane antigen; CD antigen CD8a
Species Rattus norvegicus (Rat)
Expression Region 27-236
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule
Gene References into Functions
  1. Peripheral blood CD8alphaalpha+CD11c+CD3- cells of Lewis rats were able to terminate ongoing autoimmune inflammation in the glomeruli. PMID: 24257693
  2. Recovery from Antiglomerular Basement Membrane Glomerulonephritis Is Associated with Glomeruli-Infiltrating CD8alpha+CD11c+MHC Class II+ Cells PMID: 22068125
  3. Two spondylarthritis phenotypes previously observed in different B27/Hubeta(2)m-transgenic lines also occurred in the respective CD8a(-/-)-transgenic rat lines. There was no difference in disease prevalence between CD8a(-/-) rats and CD8a(+/-) rats. PMID: 19565478
Subcellular Location Cell membrane, Single-pass type I membrane protein
Database Links

KEGG: rno:24930

STRING: 10116.ENSRNOP00000009516

UniGene: Rn.10306


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