CD8A, also known as differentiated group 8A, is expressed during T cell development and maturation, serving as a vital T cell surface biomarker. CD8A, interacting with MHC class I molecules and TCR as a co-receptor, enhances T cell antigen recognition and cytotoxic functions. It holds significant potential in tumor immunotherapy, where it can be leveraged as a therapeutic target to amplify treatment efficacy, extend treatment duration, and mitigate drug resistance, also serving as a biomarker to assess therapeutic outcomes. Overall, CD8A's multifaceted functions make it a key player in both immunology and cancer therapy.
Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial (CSB-YP004966HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP004966HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) CD8A.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP004966HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) CD8A.
CD8A Antibody (CSB-PA004966LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004966LA01HU at dilution of 1:100
The following CD8A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CD8A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004966LA01HU | CD8A Antibody | Human | ELISA, IHC |
CSB-PA004966LC01HU | CD8A Antibody, FITC conjugated | Human | |
CSB-PA004966LD01HU | CD8A Antibody, Biotin conjugated | Human | ELISA |
CSB-RA934881A0HU | CD8A Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IP |
CD8A Antibodies for Bos taurus (Bovine)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004966ZA01BO | CD8A Antibody | Bos taurus | ELISA, WB (ensure identification of antigen) |
CD8A Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP004966BO | Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Yeast |
CSB-EP004966BO | Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | E.coli |
CSB-BP004966BO CSB-MP004966BO CSB-EP004966BO-B |
Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD8A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP004966HU | Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Yeast |
CSB-EP004966HU | Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | E.coli |
CSB-MP004966HU | Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Mammalian cell |
CSB-BP004966HU CSB-EP004966HU-B |
Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Baculovirus In Vivo Biotinylation in E.coli |
CD8A Proteins for Pongo pygmaeus (Bornean orangutan)
Code | Product Name | Source |
---|---|---|
CSB-CF004966EXP | Recombinant Pongo pygmaeus T-cell surface glycoprotein CD8 alpha chain (CD8A) | in vitro E.coli expression system |
CSB-YP004966EXP1 CSB-EP004966EXP1 CSB-BP004966EXP1 CSB-MP004966EXP1 CSB-EP004966EXP1-B |
Recombinant Pongo pygmaeus T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD8A Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF004966RA | Recombinant Rat T-cell surface glycoprotein CD8 alpha chain (Cd8a) | in vitro E.coli expression system |
CSB-YP004966RA1 CSB-EP004966RA1 CSB-BP004966RA1 CSB-MP004966RA1 CSB-EP004966RA1-B |
Recombinant Rat T-cell surface glycoprotein CD8 alpha chain (Cd8a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD8A Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-CF004966DO | Recombinant Dog T-cell surface glycoprotein CD8 alpha chain (CD8A) | in vitro E.coli expression system |
CSB-YP004966DO1 CSB-BP004966DO1 CSB-MP004966DO1 CSB-EP004966DO1-B |
Recombinant Dog T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD8A Proteins for Felis catus (Cat) (Felis silvestris catus)
Code | Product Name | Source |
---|---|---|
CSB-CF004966CA | Recombinant Cat T-cell surface glycoprotein CD8 alpha chain (CD8A) | in vitro E.coli expression system |
CSB-YP004966CA1 CSB-EP004966CA1 CSB-BP004966CA1 CSB-MP004966CA1 CSB-EP004966CA1-B |
Recombinant Cat T-cell surface glycoprotein CD8 alpha chain (CD8A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD8A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF004966MO | Recombinant Mouse T-cell surface glycoprotein CD8 alpha chain (Cd8a) | in vitro E.coli expression system |
CSB-YP004966MO1 CSB-EP004966MO1 CSB-BP004966MO1 CSB-MP004966MO1 CSB-EP004966MO1-B |
Recombinant Mouse T-cell surface glycoprotein CD8 alpha chain (Cd8a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD8A ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12707h | Human Cluster of differentiation 8,CD8 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 15.6 U/mL |