ADSS Antibody

Datasheet

Code	CSB-PA001398ESR1HU
Size	US$166
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Image	Western blot All lanes: Adenylosuccinate synthetase isozyme 2 antibody at 12μg/ml Lane 1: Mouse skeletal muscle tissue Lane 2: HepG2 whole cell lysate Lane 3: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA001398ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001398ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ADSS Polyclonal antibody

Uniprot No.

P30520

Target Names

ADSS

Alternative Names

ADSS2 antibody; ADSS antibody; Adenylosuccinate synthetase isozyme 2 antibody; AMPSase 2 antibody; AdSS 2 antibody; EC 6.3.4.4 antibody; Adenylosuccinate synthetase antibody; acidic isozyme antibody; Adenylosuccinate synthetase antibody; liver isozyme antibody; L-type adenylosuccinate synthetase antibody; IMP--aspartate ligase 2 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

Gene References into Functions

Kinetic data reveal that human Ser(289) and B. subtilis Ser(262) and Ser(263) are essential for catalysis, while the ability of these Ser mutants to bind APBADP suggests that they do not contribute to substrate affinity PMID: 18469177
These findings suggest that the combined effects of the polymorphisms in the ADSS and ATM genes may confer susceptibility to the development of schizophrenia in a Chinese population PMID: 19115993

Subcellular Location

Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.

Protein Families

Adenylosuccinate synthetase family

Database Links

HGNC: 292

OMIM: 103060

KEGG: hsa:159

STRING: 9606.ENSP00000355493

UniGene: Hs.498313

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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